Ontology highlight
ABSTRACT:
SUBMITTER: Chen R
PROVIDER: S-EPMC4084668 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Chen Ron R Khatri Purvesh P Mazur Pawel K PK Polin Melanie M Zheng Yanyan Y Vaka Dedeepya D Hoang Chuong D CD Shrager Joseph J Xu Yue Y Vicent Silvestre S Butte Atul J AJ Sweet-Cordero E Alejandro EA
Cancer research 20140320 10
Lung cancer remains the most common cause of cancer-related death worldwide and it continues to lack effective treatment. The increasingly large and diverse public databases of lung cancer gene expression constitute a rich source of candidate oncogenic drivers and therapeutic targets. To define novel targets for lung adenocarcinoma, we conducted a large-scale meta-analysis of genes specifically overexpressed in adenocarcinoma. We identified an 11-gene signature that was overexpressed consistentl ...[more]