Ontology highlight
ABSTRACT:
SUBMITTER: Delcamp JH
PROVIDER: S-EPMC4084759 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20130530 23
We introduce an oxidative Heck reaction for selective complex diene and polyene formation. The reaction proceeds via oxidative Pd(II)/sulfoxide catalysis that retards palladium-hydride isomerizations which previously limited the Heck manifold's capacity for furnishing stereodefined conjugated dienes. Limiting quantities of nonactivated terminal olefins (1 equiv) and slight excesses of vinyl boronic esters (1.5 equiv) that feature diverse functionality can be used to furnish complex dienes and po ...[more]