Ontology highlight
ABSTRACT:
SUBMITTER: Wu HX
PROVIDER: S-EPMC4085486 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Wu Hai-Xia HX Jin Li-Ping LP Xu Bing B Liang Shan-Shan SS Li Da-Jin DJ
Cellular & molecular immunology 20140317 3
T helper 17 (Th17) cells have both regulatory and protective roles in physiological conditions. The Th17 subset and the cytokine interleukin-17A (IL-17A) have been implicated in the pathogenesis of certain autoimmune diseases, several types of cancer and allograft rejection. However, the role of Th17 cells at the maternal/fetal interface remains unknown. Here, we demonstrate that Th17 cells are present in decidua and are increased in the peripheral blood of 10 clinically normal pregnancies based ...[more]