Ontology highlight
ABSTRACT:
SUBMITTER: Teipel SJ
PROVIDER: S-EPMC4086659 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Teipel Stefan J SJ Flatz Wilhelm W Ackl Nibal N Grothe Michel M Kilimann Ingo I Bokde Arun L W AL Grinberg Lea L Amaro Edson E Kljajevic Vanja V Alho Eduardo E Knels Christina C Ebert Anne A Heinsen Helmut H Danek Adrian A
Psychiatry research 20131206 3
Primary progressive aphasia (PPA) is characterized by left hemispheric frontotemporal cortical atrophy. Evidence from anatomical studies suggests that the nucleus subputaminalis (NSP), a subnucleus of the cholinergic basal forebrain, may be involved in the pathological process of PPA. Therefore, we studied the pattern of cortical and basal forebrain atrophy in 10 patients with a clinical diagnosis of PPA and 18 healthy age-matched controls using high-resolution magnetic resonance imaging (MRI). ...[more]