Ontology highlight
ABSTRACT:
SUBMITTER: Jamal-Hanjani M
PROVIDER: S-EPMC4086714 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
PLoS biology 20140708 7
The importance of intratumour genetic and functional heterogeneity is increasingly recognised as a driver of cancer progression and survival outcome. Understanding how tumour clonal heterogeneity impacts upon therapeutic outcome, however, is still an area of unmet clinical and scientific need. TRACERx (TRAcking non-small cell lung Cancer Evolution through therapy [Rx]), a prospective study of patients with primary non-small cell lung cancer (NSCLC), aims to define the evolutionary trajectories o ...[more]