Ontology highlight
ABSTRACT:
SUBMITTER: Strait CE
PROVIDER: S-EPMC4086796 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Strait Caleb E CE Blanchard Tommy C TC Hayden Benjamin Y BY
Neuron 20140529 6
Recent theories suggest that reward-based choice reflects competition between value signals in the ventromedial prefrontal cortex (vmPFC). We tested this idea by recording vmPFC neurons while macaques performed a gambling task with asynchronous offer presentation. We found that neuronal activity shows four patterns consistent with selection via mutual inhibition: (1) correlated tuning for probability and reward size, suggesting that vmPFC carries an integrated value signal; (2) anti-correlated t ...[more]