Ontology highlight
ABSTRACT:
SUBMITTER: Fuchs BC
PROVIDER: S-EPMC4086837 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Fuchs Bryan C BC Hoshida Yujin Y Fujii Tsutomu T Wei Lan L Yamada Suguru S Lauwers Gregory Y GY McGinn Christopher M CM DePeralta Danielle K DK Chen Xintong X Kuroda Toshihiko T Lanuti Michael M Schmitt Anthony D AD Gupta Supriya S Crenshaw Andrew A Onofrio Robert R Taylor Bradley B Winckler Wendy W Bardeesy Nabeel N Caravan Peter P Golub Todd R TR Tanabe Kenneth K KK
Hepatology (Baltimore, Md.) 20140228 4
<h4>Unlabelled</h4>Hepatocellular carcinoma (HCC) is the most rapidly increasing cause of cancer-related mortality in the United States. Because of the lack of viable treatment options for HCC, prevention in high-risk patients has been proposed as an alternative strategy. The main risk factor for HCC is cirrhosis and several lines of evidence implicate epidermal growth factor (EGF) in the progression of cirrhosis and development of HCC. We therefore examined the effects of the EGF receptor (EGFR ...[more]