Tracking of multimodal therapeutic nanocomplexes targeting breast cancer in vivo.
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ABSTRACT:
SUBMITTER: Bardhan R
PROVIDER: S-EPMC4089981 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Publications
Tracking of multimodal therapeutic nanocomplexes targeting breast cancer in vivo.
Bardhan Rizia R Chen Wenxue W Bartels Marc M Perez-Torres Carlos C Botero Maria F MF McAninch Robin Ward RW Contreras Alejandro A Schiff Rachel R Pautler Robia G RG Halas Naomi J NJ Joshi Amit A
Nano letters 20101122 12
Nanoparticle-based therapeutics with local delivery and external electromagnetic field modulation holds extraordinary promise for soft-tissue cancers such as breast cancer; however, knowledge of the distribution and fate of nanoparticles in vivo is crucial for clinical translation. Here we demonstrate that multiple diagnostic capabilities can be introduced in photothermal therapeutic nanocomplexes by simultaneously enhancing both near-infrared fluorescence and magnetic resonance imaging (MRI). W ...[more]
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