Ontology highlight
ABSTRACT:
SUBMITTER: Liu S
PROVIDER: S-EPMC4089990 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Liu Shiping S Lorenzen Eline D ED Fumagalli Matteo M Li Bo B Harris Kelley K Xiong Zijun Z Zhou Long L Korneliussen Thorfinn Sand TS Somel Mehmet M Babbitt Courtney C Wray Greg G Li Jianwen J He Weiming W Wang Zhuo Z Fu Wenjing W Xiang Xueyan X Morgan Claire C CC Doherty Aoife A O'Connell Mary J MJ McInerney James O JO Born Erik W EW Dalén Love L Dietz Rune R Orlando Ludovic L Sonne Christian C Zhang Guojie G Nielsen Rasmus R Willerslev Eske E Wang Jun J
Cell 20140501 4
Polar bears are uniquely adapted to life in the High Arctic and have undergone drastic physiological changes in response to Arctic climates and a hyper-lipid diet of primarily marine mammal prey. We analyzed 89 complete genomes of polar bear and brown bear using population genomic modeling and show that the species diverged only 479-343 thousand years BP. We find that genes on the polar bear lineage have been under stronger positive selection than in brown bears; nine of the top 16 genes under s ...[more]