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Measurement of the time-resolved reflection matrix for enhancing light energy delivery into a scattering medium.

ABSTRACT: Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-gated detection. From this matrix, we derive and experimentally implement an incident wave pattern that optimizes the detected signal corresponding to a specific arrival time. This leads to enhanced light delivery at the target depth. The proposed method will lay a foundation for efficient phototherapy and deep-tissue in vivo imaging in the near future.

SUBMITTER: Choi Y

PROVIDER: S-EPMC4092257 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature

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Measurement of the time-resolved reflection matrix for enhancing light energy delivery into a scattering medium.

Choi Youngwoon Y Hillman Timothy R TR Choi Wonjun W Lue Niyom N Dasari Ramachandra R RR So Peter T C PT Choi Wonshik W Yaqoob Zahid Z

Physical review letters 20131209 24

Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-gated detection. From this matrix, we derive and experimentally implement an incident wave pattern that optimizes the detected signal corresponding to a specific arrival time. This leads to enhanced l ...[more]

PMID: 24483661

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