Heart failure with preserved ejection fraction: molecular pathways of the aging myocardium.
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ABSTRACT:
SUBMITTER: Loffredo FS
PROVIDER: S-EPMC4094348 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Heart failure with preserved ejection fraction: molecular pathways of the aging myocardium.
Loffredo Francesco S FS Nikolova Andriana P AP Pancoast James R JR Lee Richard T RT
Circulation research 20140601 1
Age-related diastolic dysfunction is a major factor in the epidemic of heart failure. In patients hospitalized with heart failure, HFpEF is now as common as heart failure with reduced ejection fraction. We now have many successful treatments for heart failure with reduced ejection fraction, while specific treatment options for HFpEF patients remain elusive. The lack of treatments for HFpEF reflects our very incomplete understanding of this constellation of diseases. There are many pathophysiolog ...[more]
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