Triple comorbid trajectories of tobacco, alcohol, and marijuana use as predictors of antisocial personality disorder and generalized anxiety disorder among urban adults.

ABSTRACT: We modeled triple trajectories of tobacco, alcohol, and marijuana use from adolescence to adulthood as predictors of antisocial personality disorder (ASPD) and generalized anxiety disorder (GAD).We assessed urban African American and Puerto Rican participants (n?=?816) in the Harlem Longitudinal Development Study, a psychosocial investigation, at 4 time waves (mean ages?=?19, 24, 29, and 32 years). We used Mplus to obtain the 3 variable trajectories of tobacco, alcohol, and marijuana use from time 2 to time 5 and then conducted logistic regression analyses.A 5-trajectory group model, ranging from the use of all 3 substances (23%) to a nonuse group (9%), best fit the data. Membership in the trajectory group that used all 3 substances was associated with an increased likelihood of both ASPD (adjusted odds ratio [AOR]?=?6.83; 95% CI?=?1.14, 40.74; P?

SUBMITTER: Brook JS 

PROVIDER: S-EPMC4096323 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature