Dataset Information

Genome sequencing, annotation and comparative genomic analysis of Shigella dysenteriae strain SD1D.

ABSTRACT: BACKGROUND:Shigellosis is an acute form of gastroenteritis caused by the bacteria belonging to the genus Shigella. It is the most common cause of morbidity and mortality in children. Shigella belongs to the family Enterobactericeae, which is a Gram-negative and rod shaped bacterium. In the present study, we report the draft genome of Shigella dysenteriae strain SD1D, which was isolated from the stool sample of a healthy individual. RESULTS:Based on 16S rRNA gene sequence and phylogenetic analysis, the strain SD1D was identified as Shigella dysenteriae. The draft genome of SD1D consisted of 45, 93, 159 bp with a G?+?C content of 50.7%, 4, 960 predicted CDSs, 75 tRNAs and 2 rRNAs. The final assembly contained 146 contigs of total length 45, 93, 159 bp with N50 contig length of 77, 053 bp; the largest contig assembled measured 3, 85, 550 bp. CONCLUSIONS:We have for the first time performed the whole genome sequencing of Shigella dysenteriae strain SD1D. The comparative genomic analysis revealed several genes responsible for the pathogenesis, virulence, defense, resistance to antibiotics and toxic compounds, multidrug resistance efflux pumps and other genomic features of the bacterium.

SUBMITTER: Kaur G

PROVIDER: S-EPMC4099087 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Genome sequencing, annotation and comparative genomic analysis of Shigella dysenteriae strain SD1D.

Kaur Gurwinder G Sathyabama Sathyaseelan S Arora Amit A Verma Sheenam S Mubin Nida N Agrewala Javed N JN Mayilraj Shanmugam S

Gut pathogens 20140711

<h4>Background</h4>Shigellosis is an acute form of gastroenteritis caused by the bacteria belonging to the genus Shigella. It is the most common cause of morbidity and mortality in children. Shigella belongs to the family Enterobactericeae, which is a Gram-negative and rod shaped bacterium. In the present study, we report the draft genome of Shigella dysenteriae strain SD1D, which was isolated from the stool sample of a healthy individual.<h4>Results</h4>Based on 16S rRNA gene sequence and phylo ...[more]

PMID: 25028600

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Dataset Information

Genome sequencing, annotation and comparative genomic analysis of Shigella dysenteriae strain SD1D.

Publications

Genome sequencing, annotation and comparative genomic analysis of Shigella dysenteriae strain SD1D.

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