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SFannotation: A Simple and Fast Protein Function Annotation System.

ABSTRACT: Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation. Putative proteins are typically annotated using a functional annotation system that uses extant databases, but the expansive size of these databases often causes a bottleneck for rapid functional annotation. We developed SFannotation, a simple and fast functional annotation system that rapidly annotates putative proteins against four extant databases, Swiss-Prot, TIGRFAMs, Pfam, and the non-redundant sequence database, by using a best-hit approach with BLASTP and HMMSEARCH.

SUBMITTER: Yu DS

PROVIDER: S-EPMC4099352 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature

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SFannotation: A Simple and Fast Protein Function Annotation System.

Yu Dong Su DS Kim Byung Kwon BK

Genomics & informatics 20140630 2

Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation. Putative proteins are typically annotated using a functional annotation system that uses extant databases, but the expansive size of these databases often causes a bottleneck for rapid functional annotation. We developed SFannotation, a simple and fa ...[more]

PMID: 25031571

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