Ontology highlight
ABSTRACT:
SUBMITTER: Witt CA
PROVIDER: S-EPMC4100072 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Witt Chad A CA Sheshadri Ajay A Carlstrom Luke L Tarsi Jaime J Kozlowski James J Wilson Brad B Gierada David S DS Hoffman Eric E Fain Sean B SB Cook-Granroth Janice J Sajol Geneline G Sierra Oscar O Giri Tusar T O'Neill Michael M Zheng Jie J Schechtman Kenneth B KB Bacharier Leonard B LB Jarjour Nizar N Busse William W Castro Mario M
Academic radiology 20140801 8
<h4>Rationale and objectives</h4>Previous cross-sectional studies have demonstrated that airway wall thickness and air trapping are greater in subjects with severe asthma than in those with mild-to-moderate asthma. However, a better understanding of how airway remodeling and lung density change over time is needed. This study aimed to evaluate predictors of airway wall remodeling and change in lung function and lung density over time in severe asthma.<h4>Materials and methods</h4>Phenotypic char ...[more]