Ontology highlight
ABSTRACT:
SUBMITTER: Lee S
PROVIDER: S-EPMC4100076 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Lee Soohyun S Kruglikov Illya I Huang Z Josh ZJ Fishell Gord G Rudy Bernardo B
Nature neuroscience 20131006 11
The influence of motor activity on sensory processing is crucial for perception and motor execution. However, the underlying circuits are not known. To unravel the circuit by which activity in the primary vibrissal motor cortex (vM1) modulates sensory processing in the primary somatosensory barrel cortex (S1), we used optogenetics to examine the long-range inputs from vM1 to the various neuronal elements in S1. We found that S1-projecting vM1 pyramidal neurons strongly recruited vasointestinal p ...[more]