Ontology highlight
ABSTRACT:
SUBMITTER: Witchley JN
PROVIDER: S-EPMC4101538 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Witchley Jessica N JN Mayer Mirjam M Wagner Daniel E DE Owen Jared H JH Reddien Peter W PW
Cell reports 20130815 4
Regeneration requires both potential and instructions for tissue replacement. In planarians, pluripotent stem cells have the potential to produce all new tissue. The identities of the cells that provide regeneration instructions are unknown. Here, we report that position control genes (PCGs) that control regeneration and tissue turnover are expressed in a subepidermal layer of nonneoblast cells. These subepidermal cells coexpress many PCGs. We propose that these subepidermal cells provide a syst ...[more]