Ontology highlight
ABSTRACT:
SUBMITTER: Janso JE
PROVIDER: S-EPMC4101813 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Janso Jeffrey E JE Haltli Brad A BA Eustáquio Alessandra S AS Kulowski Kerry K Waldman Abraham J AJ Zha Li L Nakamura Hitomi H Bernan Valerie S VS He Haiyin H Carter Guy T GT Koehn Frank E FE Balskus Emily P EP
Tetrahedron 20140701 27-28
The lomaiviticins are a family of cytotoxic marine natural products that have captured the attention of both synthetic and biological chemists due to their intricate molecular scaffolds and potent biological activities. Here we describe the identification of the gene cluster responsible for lomaiviticin biosynthesis in <i>Salinispora pacifica</i> strains DPJ-0016 and DPJ-0019 using a combination of molecular approaches and genome sequencing. The link between the <i>lom</i> gene cluster and lomai ...[more]