Ontology highlight
ABSTRACT:
SUBMITTER: Huang SX
PROVIDER: S-EPMC4101921 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Huang Sarah X L SX Islam Mohammad Naimul MN O'Neill John J Hu Zheng Z Yang Yong-Guang YG Chen Ya-Wen YW Mumau Melanie M Green Michael D MD Vunjak-Novakovic Gordana G Bhattacharya Jahar J Snoeck Hans-Willem HW
Nature biotechnology 20131201 1
The ability to generate lung and airway epithelial cells from human pluripotent stem cells (hPSCs) would have applications in regenerative medicine, modeling of lung disease, drug screening and studies of human lung development. We have established, based on developmental paradigms, a highly efficient method for directed differentiation of hPSCs into lung and airway epithelial cells. Long-term differentiation of hPSCs in vivo and in vitro yielded basal, goblet, Clara, ciliated, type I and type I ...[more]