Ontology highlight
ABSTRACT:
SUBMITTER: Lin G
PROVIDER: S-EPMC4102941 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Lin G G Hill D K DK Andrejeva G G Boult J K R JK Troy H H Fong A-C L F W T AC Orton M R MR Panek R R Parkes H G HG Jafar M M Koh D-M DM Robinson S P SP Judson I R IR Griffiths J R JR Leach M O MO Eykyn T R TR Chung Y-L YL
British journal of cancer 20140603 2
<h4>Background</h4>Dichloroacetate (DCA) has been found to have antitumour properties.<h4>Methods</h4>We investigated the cellular and metabolic responses to DCA treatment and recovery in human colorectal (HT29, HCT116 WT and HCT116 Bax-ko), prostate carcinoma cells (PC3) and HT29 xenografts by flow cytometry, western blotting, electron microscopy, (1)H and hyperpolarised (13)C-magnetic resonance spectroscopy.<h4>Results</h4>Increased expression of the autophagy markers LC3B II was observed foll ...[more]