Ontology highlight
ABSTRACT:
SUBMITTER: Yakhnina AA
PROVIDER: S-EPMC4105008 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Yakhnina Anastasiya A AA Gitai Zemer Z
Molecular microbiology 20120725 6
In Caulobacter crescentus, the actin homologue MreB is critical for cell shape maintenance. Despite the central importance of MreB for cell morphology and viability, very little is known about MreB-interacting factors. Here, we use an overexpression approach to identify a novel MreB interactor, MbiA. MbiA interacts with MreB in both biochemical and genetic assays, colocalizes with MreB throughout the cell cycle, and relies on MreB for its localization. MbiA overexpression mimics the loss of MreB ...[more]