Ontology highlight
ABSTRACT:
SUBMITTER: Chen LC
PROVIDER: S-EPMC4106121 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Chen Leng-Chun LC Lloyd William R WR Kuo Shiuhyang S Kim Hyungjin Myra HM Marcelo Cynthia L CL Feinberg Stephen E SE Mycek Mary-Ann MA
Biomaterials 20140520 25
Nonlinear optical molecular imaging and quantitative analytic methods were developed to non-invasively assess the viability of tissue-engineered constructs manufactured from primary human cells. Label-free optical measures of local tissue structure and biochemistry characterized morphologic and functional differences between controls and stressed constructs. Rigorous statistical analysis accounted for variability between human patients. Fluorescence intensity-based spatial assessment and metabol ...[more]