Surgical vs medical treatments for type 2 diabetes mellitus: a randomized clinical trial.

ABSTRACT:

Importance

Many questions remain unanswered about the role of bariatric surgery for people with type 2 diabetes mellitus (T2DM).

Objective

To determine feasibility of a randomized clinical trial (RCT) and compare initial outcomes of bariatric surgery and a structured weight loss program for treating T2DM in participants with grades I and II obesity.

Design, setting, and participants

A 12-month, 3-arm RCT at a single center including 69 participants aged 25 to 55 years with a body mass index (calculated as weight in kilograms divided by height in meters squared) of 30 to 40 and T2DM.

Interventions

Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric banding (LAGB), and an intensive lifestyle weight loss intervention (LWLI).

Main outcomes and measu

SUBMITTER: Courcoulas AP 

PROVIDER: S-EPMC4106661 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature