Ontology highlight
ABSTRACT:
SUBMITTER: Litwin-Kumar A
PROVIDER: S-EPMC4106684 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Litwin-Kumar Ashok A Doiron Brent B
Nature neuroscience 20120923 11
Anatomical studies demonstrate that excitatory connections in cortex are not uniformly distributed across a network but instead exhibit clustering into groups of highly connected neurons. The implications of clustering for cortical activity are unclear. We studied the effect of clustered excitatory connections on the dynamics of neuronal networks that exhibited high spike time variability owing to a balance between excitation and inhibition. Even modest clustering substantially changed the behav ...[more]