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ABSTRACT:
SUBMITTER: Pokkuluri PR
PROVIDER: S-EPMC4109977 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Pokkuluri P R PR Yang X X Londer Y Y YY Schiffer M M
Journal of structural and functional genomics 20121026 4
PpcA is a small protein with 71 residues that contains three covalently bound hemes. The structures of single mutants at residue 58 have shown larger deviations in another part of the protein molecule than at the site of the mutation. Closer examination of the crystal packing has revealed the origin of this unexpected structural change. The site of mutation is within Van der Waals distance from another protein molecule related by a crystallographic twofold axis within the crystal. The structural ...[more]