Ontology highlight
ABSTRACT:
SUBMITTER: McCormick C
PROVIDER: S-EPMC4110351 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
McCormick Cornelia C Protzner Andrea B AB Barnett Alexander J AJ Cohn Melanie M Valiante Taufik A TA McAndrews Mary Pat MP
NeuroImage. Clinical 20140516
Computational models predict that focal damage to the Default Mode Network (DMN) causes widespread decreases and increases of functional DMN connectivity. How such alterations impact functioning in a specific cognitive domain such as episodic memory remains relatively unexplored. Here, we show in patients with unilateral medial temporal lobe epilepsy (mTLE) that focal structural damage leads indeed to specific patterns of DMN functional connectivity alterations, specifically decreased connectivi ...[more]