Ontology highlight
ABSTRACT:
SUBMITTER: Beemelmanns C
PROVIDER: S-EPMC4111216 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Beemelmanns Christine C Woznica Arielle A Alegado Rosanna A RA Cantley Alexandra M AM King Nicole N Clardy Jon J
Journal of the American Chemical Society 20140710 29
Studies on the origin of animal multicellularity have increasingly focused on one of the closest living relatives of animals, the choanoflagellate Salpingoeca rosetta. Single cells of S. rosetta can develop into multicellular rosette-shaped colonies through a process of incomplete cytokinesis. Unexpectedly, the initiation of rosette development requires bacterially produced small molecules. Previously, our laboratories reported the planar structure and femtomolar rosette-inducing activity of one ...[more]