Ontology highlight
ABSTRACT:
SUBMITTER: Maniti O
PROVIDER: S-EPMC4111548 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Maniti Ofelia O Khalifat Nada N Goggia Kriti K Dalonneau Fabien F Guérin Christophe C Blanchoin Laurent L Ramos Laurence L Picart Catherine C Picart Catherine C
Biochimica et biophysica acta 20120716 11
The plasma membrane-cytoskeleton interface is a dynamic structure participating in a variety of cellular events. Moesin and ezrin, proteins from the ezrin/radixin/moesin (ERM) family, provide a direct linkage between the cytoskeleton and the membrane via their interaction with phosphatidylinositol 4,5-bisphosphate (PIP(2)). PIP(2) binding is considered as a prerequisite step in ERM activation. The main objective of this work was to compare moesin and ezrin interaction with PIP(2)-containing memb ...[more]