Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC4112407 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Li Jia J Yang James J Levin Albert M AM Montgomery Courtney G CG Datta Indrani I Trudeau Sheri S Adrianto Indra I McKeigue Paul P Iannuzzi Michael C MC Rybicki Benjamin A BA
Genetic epidemiology 20140520 5
Genome-wide association studies (GWAS) that draw samples from multiple studies with a mixture of relationship structures are becoming more common. Analytical methods exist for using mixed-sample data, but few methods have been proposed for the analysis of genotype-by-environment (G×E) interactions. Using GWAS data from a study of sarcoidosis susceptibility genes in related and unrelated African Americans, we explored the current analytic options for genotype association testing in studies using ...[more]