Ontology highlight
ABSTRACT:
SUBMITTER: Garrido-Maraver J
PROVIDER: S-EPMC4112525 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Garrido-Maraver Juan J Cordero Mario D MD Oropesa-Ávila Manuel M Fernández Vega Alejandro A de la Mata Mario M Delgado Pavón Ana A de Miguel Manuel M Pérez Calero Carmen C Villanueva Paz Marina M Cotán David D Sánchez-Alcázar José A JA
Molecular syndromology 20140701 3-4
For a number of years, coenzyme Q10 (CoQ10) was known for its key role in mitochondrial bioenergetics; later studies demonstrated its presence in other subcellular fractions and in blood plasma, and extensively investigated its antioxidant role. These 2 functions constitute the basis for supporting the clinical use of CoQ10. Also, at the inner mitochondrial membrane level, CoQ10 is recognized as an obligatory cofactor for the function of uncoupling proteins and a modulator of the mitochondrial t ...[more]