Behavioral and neurophysiological correlates of regret in rat decision-making on a neuroeconomic task.
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ABSTRACT:
SUBMITTER: Steiner AP
PROVIDER: S-EPMC4113023 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
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Behavioral and neurophysiological correlates of regret in rat decision-making on a neuroeconomic task.
Steiner Adam P AP Redish A David AD
Nature neuroscience 20140608 7
Disappointment entails the recognition that one did not get the value expected. In contrast, regret entails recognition that an alternative (counterfactual) action would have produced a more valued outcome. In humans, the orbitofrontal cortex is active during expressions of regret, and humans with damage to the orbitofrontal cortex do not express regret. In rats and nonhuman primates, both the orbitofrontal cortex and the ventral striatum have been implicated in reward computations. We recorded ...[more]
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