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Comparative primate genomics: emerging patterns of genome content and dynamics.


ABSTRACT: Advances in genome sequencing technologies have created new opportunities for comparative primate genomics. Genome assemblies have been published for various primate species, and analyses of several others are underway. Whole-genome assemblies for the great apes provide remarkable new information about the evolutionary origins of the human genome and the processes involved. Genomic data for macaques and other non-human primates offer valuable insights into genetic similarities and differences among species that are used as models for disease-related research. This Review summarizes current knowledge regarding primate genome content and dynamics, and proposes a series of goals for the near future.

SUBMITTER: Rogers J 

PROVIDER: S-EPMC4113315 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature

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Comparative primate genomics: emerging patterns of genome content and dynamics.

Rogers Jeffrey J   Gibbs Richard A RA  

Nature reviews. Genetics 20140408 5


Advances in genome sequencing technologies have created new opportunities for comparative primate genomics. Genome assemblies have been published for various primate species, and analyses of several others are underway. Whole-genome assemblies for the great apes provide remarkable new information about the evolutionary origins of the human genome and the processes involved. Genomic data for macaques and other non-human primates offer valuable insights into genetic similarities and differences am  ...[more]

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