Ontology highlight
ABSTRACT:
SUBMITTER: Hill KE
PROVIDER: S-EPMC4113432 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Hill Kristina E KE Motley Amy K AK Winfrey Virginia P VP Burk Raymond F RF
PloS one 20140728 7
Selenium is transferred from the mouse dam to its neonate via milk. Milk contains selenium in selenoprotein form as selenoprotein P (Sepp1) and glutathione peroxidase-3 (Gpx3) as well as in non-specific protein form as selenomethionine. Selenium is also present in milk in uncharacterized small-molecule form. We eliminated selenomethionine from the mice in these experiments by feeding a diet that contained sodium selenite as the source of selenium. Selenium-replete dams with deletion of Sepp1 or ...[more]