Dataset Information

Intracerebral hemorrhage mortality is not changing despite declining incidence.

ABSTRACT:

Objective

To determine trends in incidence and mortality of intracerebral hemorrhage (ICH) in a rigorous population-based study.

Methods

We identified all cases of spontaneous ICH in a South Texas community from 2000 to 2010 using rigorous case ascertainment methods within the Brain Attack Surveillance in Corpus Christi Project. Yearly population counts were determined from the US Census, and deaths were determined from state and national databases. Age-, sex-, and ethnicity-adjusted incidence was estimated for each year with Poisson regression, and a linear trend over time was investigated. Trends in 30-day case fatality and long-term mortality (censored at 3 years) were estimated with log-binomial or Cox proportional hazards models adjusted for demographics, stroke severity, and comorbid disease.

Results

A total of 734 cases of ICH were included. The age-, sex-, and ethnicity-adjusted ICH annual incidence rate was 5.21 per 10,000 (95% confidence interval [CI] 4.36, 6.24) in 2000 and 4.30 per 10,000 (95% CI 3.21, 5.76) in 2010. The estimated 10-year change in demographic-adjusted ICH annual incidence rate was -31% (95% CI -47%, -11%). Yearly demographic-adjusted 30-day case fatality ranged from 28.3% (95% CI 19.9%, 40.3%) in 2006 to 46.5% (95% CI 35.5, 60.8) in 2008. There was no change in ICH case fatality or long-term mortality over time.

Conclusions

ICH incidence decreased over the past decade, but case fatality and long-term mortality were unchanged. This suggests that primary prevention efforts may be improving over time, but more work is needed to improve ICH treatment and reduce the risk of death.

SUBMITTER: Zahuranec DB

PROVIDER: S-EPMC4113463 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Intracerebral hemorrhage mortality is not changing despite declining incidence.

Zahuranec Darin B DB Lisabeth Lynda D LD Sánchez Brisa N BN Smith Melinda A MA Brown Devin L DL Garcia Nelda M NM Skolarus Lesli E LE Meurer William J WJ Burke James F JF Adelman Eric E EE Morgenstern Lewis B LB

Neurology 20140516 24

<h4>Objective</h4>To determine trends in incidence and mortality of intracerebral hemorrhage (ICH) in a rigorous population-based study.<h4>Methods</h4>We identified all cases of spontaneous ICH in a South Texas community from 2000 to 2010 using rigorous case ascertainment methods within the Brain Attack Surveillance in Corpus Christi Project. Yearly population counts were determined from the US Census, and deaths were determined from state and national databases. Age-, sex-, and ethnicity-adjus ...[more]

PMID: 24838789

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Dataset Information

Intracerebral hemorrhage mortality is not changing despite declining incidence.

Objective

Methods

Results

Conclusions

Publications

Intracerebral hemorrhage mortality is not changing despite declining incidence.

Similar Datasets

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