Membranous replication factories induced by plus-strand RNA viruses.
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ABSTRACT:
SUBMITTER: Romero-Brey I
PROVIDER: S-EPMC4113795 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Publications
Membranous replication factories induced by plus-strand RNA viruses.
Romero-Brey Inés I Bartenschlager Ralf R
Viruses 20140722 7
In this review, we summarize the current knowledge about the membranous replication factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of these complex membrane rearrangements, because this topic emerged in the last few years as electron tomography has become more widely available. A general denominator is that two "morphotypes" of membrane alterations can be found that are exemplified by flaviviruses and hepaciviruses: membrane invaginations towards the l ...[more]
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