Chemical sensing by nonequilibrium cooperative receptors.
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ABSTRACT:
SUBMITTER: Skoge M
PROVIDER: S-EPMC4114058 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Publications
Chemical sensing by nonequilibrium cooperative receptors.
Skoge Monica M Naqvi Sahin S Meir Yigal Y Wingreen Ned S NS
Physical review letters 20130611 24
Cooperativity arising from local interactions in equilibrium receptor systems provides gain, but does not increase sensory performance, as measured by the signal-to-noise ratio (SNR) due to a fundamental tradeoff between gain and intrinsic noise. Here we allow sensing to be a nonequilibrium process and show that energy dissipation cannot circumvent the fundamental tradeoff, so that the SNR is still optimal for independent receptors. For systems requiring high gain, nonequilibrium 2D-coupled rece ...[more]
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