Ontology highlight
ABSTRACT:
SUBMITTER: Meck C
PROVIDER: S-EPMC4114738 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Meck Christine C D'Erasmo Michael P MP Hirsch Danielle R DR Murelli Ryan P RP
MedChemComm 20140701 7
α-Hydroxytropolones are a subclass of the troponoid family of natural products that are of high interest due to their broad biological activity and potential as treatment options for several diseases. Despite this promise, there have been scarce synthetic chemistry-driven optimization studies on the molecules. The following review highlights key developments in the biological studies conducted on α-hydroxytropolones to date, including the few synthetic chemistry-driven optimization studies. In a ...[more]