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Molluscum contagiosum in a pediatric American Indian population: incidence and risk factors.


ABSTRACT:

Background

Molluscum contagiosum virus (MCV) causes an innocuous yet persistent skin infection in immunocompetent individuals and is spread by contact with lesions. Studies point to atopic dermatitis (AD) as a risk factor for MCV infection; however, there are no longitudinal studies that have evaluated this hypothesis.

Methods

Outpatient visit data from fiscal years 2001-2009 for American Indian and Alaska Native (AI/AN) children were examined to describe the incidence of molluscum contagiosum (MC). We conducted a case-control study of patients <5 years old at an Indian Health Service (IHS) clinic to evaluate dermatological risk factors for infection.

Results

The incidence rate for MC in children <5 years old was highest in the West and East regions. MC cases were more likely to have a prior or co-occurring diagnosis of eczema, eczema or dermatitis, impetigo, and scabies (p<0.05) compared to controls; 51.4% of MC cases had a prior or co-occurring diagnosis of eczema or dermatitis.

Conclusions

The present study is the first demonstration of an association between AD and MC using a case-control study design. It is unknown if the concurrent high incidence of eczema and MC is related, and this association deserves further investigation.

SUBMITTER: McCollum AM 

PROVIDER: S-EPMC4114779 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Molluscum contagiosum in a pediatric American Indian population: incidence and risk factors.

McCollum Andrea M AM   Holman Robert C RC   Hughes Christine M CM   Mehal Jason M JM   Folkema Arianne M AM   Redd John T JT   Cheek James E JE   Damon Inger K IK   Reynolds Mary G MG  

PloS one 20140729 7


<h4>Background</h4>Molluscum contagiosum virus (MCV) causes an innocuous yet persistent skin infection in immunocompetent individuals and is spread by contact with lesions. Studies point to atopic dermatitis (AD) as a risk factor for MCV infection; however, there are no longitudinal studies that have evaluated this hypothesis.<h4>Methods</h4>Outpatient visit data from fiscal years 2001-2009 for American Indian and Alaska Native (AI/AN) children were examined to describe the incidence of molluscu  ...[more]

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