Ontology highlight
ABSTRACT:
SUBMITTER: Halbroth BR
PROVIDER: S-EPMC4114834 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Halbroth Benedict R BR Heil Alexander A Distler Eva E Dass Martin M Wagner Eva M EM Plachter Bodo B Probst Hans Christian HC Strand Dennis D Hartwig Udo F UF Karner Anita A Aichinger Gerald G Kistner Otfried O Landfester Katharina K Herr Wolfgang W
PloS one 20140729 7
Pandemic and seasonal influenza viruses cause considerable morbidity and mortality in the general human population. Protection from severe disease may result from vaccines that activate antigen-presenting DC for effective stimulation of influenza-specific memory T cells. Special attention is paid to vaccine-induced CD8+ T-cell responses, because they are mainly directed against conserved internal influenza proteins thereby presumably mediating cross-protection against circulating seasonal as wel ...[more]