Neuropathic pain: role of inflammation, immune response, and ion channel activity in central injury mechanisms.
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ABSTRACT:
SUBMITTER: Schomberg D
PROVIDER: S-EPMC4117080 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Publications
Neuropathic pain: role of inflammation, immune response, and ion channel activity in central injury mechanisms.
Schomberg Dominic D Ahmed Mostafa M Miranpuri Gurwattan G Olson Julie J Resnick Daniel K DK
Annals of neurosciences 20120701 3
Neuropathic pain (NP) is a significant and disabling clinical problem with very few therapeutic treatment options available. A major priority is to identify the molecular mechanisms responsible for NP. Although many seemingly relevant pathways have been identified, more research is needed before effective clinical interventions can be produced. Initial insults to the nervous system, such as spinal cord injury (SCI), are often compounded by secondary mechanisms such as inflammation, the immune re ...[more]
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