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Genome sequence of tumor virus x, a member of the genus protoparvovirus in the family parvoviridae.


ABSTRACT: The orphan parvovirus tumor virus X (TVX) has potent oncolytic activity. Compared to other viruses from the species Rodent protoparvovirus 1, TVX has a 111 nucleotide deletion in its nonstructural (NS) gene, a 24 nucleotide insertion in VP1, and a 93 nucleotide repeat initiating from the C-terminus of the capsid gene.

SUBMITTER: Vollmers EM 

PROVIDER: S-EPMC4118071 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Genome sequence of tumor virus x, a member of the genus protoparvovirus in the family parvoviridae.

Vollmers Ellen M EM   D'Abramo Anthony A   Cotmore Susan F SF   Tattersall Peter P  

Genome announcements 20140731 4


The orphan parvovirus tumor virus X (TVX) has potent oncolytic activity. Compared to other viruses from the species Rodent protoparvovirus 1, TVX has a 111 nucleotide deletion in its nonstructural (NS) gene, a 24 nucleotide insertion in VP1, and a 93 nucleotide repeat initiating from the C-terminus of the capsid gene. ...[more]

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