Ontology highlight
ABSTRACT:
SUBMITTER: Reynoso R
PROVIDER: S-EPMC4118195 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Scientific reports 20140801
Elite controllers maintain HIV-1 viral loads below the limit of detection. The mechanisms responsible for this phenomenon are poorly understood. As microRNAs (miRNAs) are regulators of gene expression and some of them modulate HIV infection, we have studied the miRNA profile in plasma from HIV elite controllers and chronically infected individuals and compared against healthy donors. Several miRNAs correlate with CD4+ T cell count or with the known time of infection. No significant differences w ...[more]