Improvement of prediction ability for genomic selection of dairy cattle by including dominance effects.
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ABSTRACT: Dominance may be an important source of non-additive genetic variance for many traits of dairy cattle. However, nearly all prediction models for dairy cattle have included only additive effects because of the limited number of cows with both genotypes and phenotypes. The role of dominance in the Holstein and Jersey breeds was investigated for eight traits: milk, fat, and protein yields; productive life; daughter pregnancy rate; somatic cell score; fat percent and protein percent. Additive and dominance variance components were estimated and then used to estimate additive and dominance effects of single nucleotide polymorphisms (SNPs). The predictive abilities of three models with both additive and dominance effects and a model with additive effects only were assessed using ten-fold cross-v
SUBMITTER: Sun C
PROVIDER: S-EPMC4118992 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
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