Ontology highlight
ABSTRACT:
SUBMITTER: Hsu PL
PROVIDER: S-EPMC4119023 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Journal of molecular biology 20140618 16
The phosphorylation state of heptapeptide repeats within the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (PolII) controls the transcription cycle and is maintained by the competing action of kinases and phosphatases. Rtr1 was recently proposed to be the enzyme responsible for the transition of PolII into the elongation and termination phases of transcription by removing the phosphate marker on serine 5, but this attribution was questioned by the apparent lack of enzymatic ...[more]