Ontology highlight
ABSTRACT:
SUBMITTER: Shiozaki A
PROVIDER: S-EPMC4119626 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Shiozaki Atsushi A Takemoto Kenichi K Ichikawa Daisuke D Fujiwara Hitoshi H Konishi Hirotaka H Kosuga Toshiyuki T Komatsu Shuhei S Okamoto Kazuma K Kishimoto Mitsuo M Marunaka Yoshinori Y Otsuji Eigo E
BioMed research international 20140709
The objectives of the present study were to investigate the role of K-Cl cotransporter 3 (KCC3) in the regulation of cellular invasion and the clinicopathological significance of its expression in esophageal squamous cell carcinoma (ESCC). Immunohistochemical analysis performed on 70 primary tumor samples obtained from ESCC patients showed that KCC3 was primarily found in the cytoplasm of carcinoma cells. Although the expression of KCC3 in the main tumor (MT) was related to several clinicopathol ...[more]