By hook or by crook: multifaceted DNA-binding properties of MeCP2.
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ABSTRACT:
SUBMITTER: Shin J
PROVIDER: S-EPMC4119793 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Publications
By hook or by crook: multifaceted DNA-binding properties of MeCP2.
Shin Jaehoon J Ming Guo-Li GL Song Hongjun H
Cell 20130201 5
Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interacts with hydroxymethyl-CpG. ...[more]
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