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IFITMs restrict the replication of multiple pathogenic viruses.


ABSTRACT: The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis.

SUBMITTER: Perreira JM 

PROVIDER: S-EPMC4121887 | biostudies-literature |

REPOSITORIES: biostudies-literature

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