Ontology highlight
ABSTRACT:
SUBMITTER: Lo Sciuto A
PROVIDER: S-EPMC4122361 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Lo Sciuto Alessandra A Fernández-Piñar Regina R Bertuccini Lucia L Iosi Francesca F Superti Fabiana F Imperi Francesco F
PloS one 20140805 8
The Gram-negative bacterium Pseudomonas aeruginosa is one of the most dreaded pathogens in the hospital setting, and represents a prototype of multi-drug resistant "superbug" for which effective therapeutic options are very limited. The identification and characterization of new cellular functions that are essential for P. aeruginosa viability and/or virulence could drive the development of anti-Pseudomonas compounds with novel mechanisms of action. In this study we investigated whether TolB, th ...[more]