Ontology highlight
ABSTRACT:
SUBMITTER: Badoux XC
PROVIDER: S-EPMC4123422 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Badoux Xavier C XC Keating Michael J MJ Wen Sijin S Lee Bang-Ning BN Sivina Mariela M Reuben James J Wierda William G WG O'Brien Susan M SM Faderl Stefan S Kornblau Steven M SM Burger Jan A JA Ferrajoli Alessandra A
Blood 20110701 13
The best initial therapy for elderly patients with chronic lymphocytic leukemia (CLL) has not yet been defined. We investigated the activity of lenalidomide as initial therapy for elderly patients with CLL. Sixty patients with CLL 65 years of age and older received treatment with lenalidomide orally 5 mg daily for 56 days, then titrated up to 25 mg/d as tolerated. Treatment was continued until disease progression. At a median follow-up of 29 months, 53 patients (88%) are alive and 32 patients (5 ...[more]