Ontology highlight
ABSTRACT:
SUBMITTER: Figueroa JD
PROVIDER: S-EPMC4123644 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Figueroa Jonine D JD Han Summer S SS Garcia-Closas Montserrat M Baris Dalsu D Jacobs Eric J EJ Kogevinas Manolis M Schwenn Molly M Malats Nuria N Johnson Alison A Purdue Mark P MP Caporaso Neil N Landi Maria Teresa MT Prokunina-Olsson Ludmila L Wang Zhaoming Z Hutchinson Amy A Burdette Laurie L Wheeler William W Vineis Paolo P Siddiq Afshan A Cortessis Victoria K VK Kooperberg Charles C Cussenot Olivier O Benhamou Simone S Prescott Jennifer J Porru Stefano S Bueno-de-Mesquita H Bas HB Trichopoulos Dimitrios D Ljungberg Börje B Clavel-Chapelon Françoise F Weiderpass Elisabete E Krogh Vittorio V Dorronsoro Miren M Travis Ruth R Tjønneland Anne A Brenan Paul P Chang-Claude Jenny J Riboli Elio E Conti David D Gago-Dominguez Manuela M Stern Mariana C MC Pike Malcolm C MC Van Den Berg David D Yuan Jian-Min JM Hohensee Chancellor C Rodabough Rebecca R Cancel-Tassin Geraldine G Roupret Morgan M Comperat Eva E Chen Constance C De Vivo Immaculata I Giovannucci Edward E Hunter David J DJ Kraft Peter P Lindstrom Sara S Carta Angela A Pavanello Sofia S Arici Cecilia C Mastrangelo Giuseppe G Karagas Margaret R MR Schned Alan A Armenti Karla R KR Hosain G M Monawar GM Haiman Chris A CA Fraumeni Joseph F JF Chanock Stephen J SJ Chatterjee Nilanjan N Rothman Nathaniel N Silverman Debra T DT
Carcinogenesis 20140324 8
Bladder cancer is a complex disease with known environmental and genetic risk factors. We performed a genome-wide interaction study (GWAS) of smoking and bladder cancer risk based on primary scan data from 3002 cases and 4411 controls from the National Cancer Institute Bladder Cancer GWAS. Alternative methods were used to evaluate both additive and multiplicative interactions between individual single nucleotide polymorphisms (SNPs) and smoking exposure. SNPs with interaction P values < 5 × 10(- ...[more]